Chez Spironolactone 50mg Tablet x28

Chez Spironolactone 50mg Tablet contains Spironolactone, a potassium-sparing diuretic and aldosterone receptor antagonist. This medication treats fluid retention, high blood pressure, heart failure, and hormonal conditions like hirsutism and acne.

Uses

Chez Spironolactone treats edema associated with heart failure, liver cirrhosis, and kidney disease. It manages hypertension, primary hyperaldosteronism, and low potassium levels. In women, it treats hormonal acne, hirsutism, and androgenetic alopecia by blocking androgen receptors.

Benefits

• Reduces fluid retention and swelling
• Lowers blood pressure effectively
• Preserves potassium levels unlike other diuretics
• Improves heart failure symptoms and survival
• Reduces hormonal acne in women
• Decreases excessive hair growth (hirsutism)
• Helps with female pattern hair loss
• Protects against potassium depletion
• Provides cardioprotective effects in heart failure

How It Works

Chez Spironolactone blocks aldosterone receptors in the kidneys, reducing sodium and water retention while preserving potassium. It also blocks androgen receptors, reducing testosterone effects on skin and hair follicles. This dual action makes it effective for both cardiovascular and dermatological conditions.

Dosage

Take with food to reduce stomach irritation. Dosage adjustments based on response and potassium levels.

Duration of Action

Chez Spironolactone begins working within hours, with peak diuretic effects occurring in 2-3 days. For hormonal conditions, improvements typically appear after 6-8 weeks, with maximum benefits achieved after 3-6 months of consistent treatment. Effects persist for 2-3 days after discontinuation.

Side Effects

Common side effects include hyperkalemia (high potassium), dizziness, headache, and gastrointestinal upset. Women may experience breast tenderness, irregular periods, or deepening voice with high doses. Men may develop gynecomastia or decreased libido. Serious effects include severe electrolyte imbalances.

Warning

Chez Spironolactone can cause dangerous hyperkalemia, especially in patients with kidney disease or those taking ACE inhibitors. Regular monitoring of potassium and kidney function is essential. Avoid potassium supplements and salt substitutes containing potassium. May cause feminizing effects in male fetuses if used during pregnancy.

Pregnancy and Breastfeeding

Spironolactone is contraindicated during pregnancy due to risk of feminization of male fetuses. Women should use effective contraception during treatment. The medication passes into breast milk and may cause hormonal effects in nursing infants, so breastfeeding is not recommended.

Interaction

• Increased hyperkalemia risk with ACE inhibitors and ARBs
• Enhanced effects when combined with other diuretics
• May increase lithium levels causing toxicity
• Reduced effectiveness of anticoagulants like warfarin
• Potassium supplements may cause dangerous hyperkalemia
• NSAIDs may reduce diuretic effects and increase kidney damage risk

Precaution

Monitor potassium levels regularly, especially during initiation and dose changes. Use cautiously in elderly patients and those with kidney or liver impairment. Avoid in patients with severe kidney disease or hyperkalemia. Regular monitoring of kidney function and electrolytes is essential throughout treatment.

Important Information

Chez Spironolactone requires regular blood tests to monitor potassium and kidney function. Avoid foods high in potassium and salt substitutes during treatment. Report symptoms of hyperkalemia including muscle weakness, irregular heartbeat, or numbness. Store at room temperature away from moisture and heat. Take consistently at the same time daily for best results.