Co-Mepiryl Forte Tablet (Glimepiride) x30

Co-Mepiryl Forte Tablet is a combination oral antidiabetic medication containing Glimepiride and Metformin. This dual-action formula effectively manages type 2 diabetes by improving blood sugar control through complementary mechanisms.

Uses

Co-Mepiryl Forte is prescribed for treating type 2 diabetes mellitus when diet, exercise, and single-drug therapy are not providing adequate blood glucose control. It’s particularly effective for patients requiring both improved insulin secretion and enhanced insulin sensitivity.

Benefits

• Provides effective blood sugar control
• Improves insulin sensitivity
• Enhances insulin production
• Reduces glucose production in liver
• Improves glucose utilization
• Helps maintain long-term diabetes control
• May assist in weight management
• Reduces diabetes complications risk
• Convenient dual-action formula

How It Works

Glimepiride stimulates insulin release from pancreatic cells, while Metformin reduces glucose production in the liver and improves insulin sensitivity in body tissues. This dual mechanism provides comprehensive blood sugar control.

Duration of Action

Initial effects begin within 1-2 weeks. Maximum therapeutic benefits typically achieved after 4-6 weeks of regular use. Effects last 24 hours with consistent daily dosing.

Dosage

Initial dosage based on current diabetes treatment:

Usually one tablet twice daily with meals

Maximum daily dose should not exceed two tablets

Take at same times each day for consistent control

Side Effects

Common side effects include mild nausea, stomach upset, diarrhea, and metallic taste. Less common effects may include low blood sugar, especially when skipping meals or during increased physical activity.

Warning

Regular blood sugar monitoring essential. Risk of hypoglycemia if meals are delayed or skipped. Avoid alcohol. Temporary discontinuation may be needed before surgery or certain medical procedures.

Pregnancy and Breastfeeding

Not recommended during pregnancy or breastfeeding. Alternative diabetes treatments should be discussed with healthcare provider for these periods.

Interactions

• May interact with other diabetes medications
• Enhanced effects with alcohol consumption
• Possible interactions with certain antibiotics
• Effects altered by steroids
• Caution with blood pressure medications

Important Information

Store Co-Mepiryl Forte below 25°C in a dry place. Take with first meal of day. Regular blood sugar monitoring required. Maintain consistent meal schedule. Carry glucose source for potential low blood sugar episodes. Regular exercise and proper diet essential for optimal results. Report any unusual symptoms to healthcare provider immediately.