Contiflo OD is a modified-release tablet containing tamsulosin hydrochloride, an alpha-blocker medication. This prescription drug alleviates urinary symptoms associated with benign prostatic hyperplasia (BPH). Its sustained-release formulation enables once-daily dosing for improved patient convenience and compliance.
Uses
Contiflo OD treats lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia. It relieves frequent urination, urgent urination, weak urine stream, difficulty starting urination, and incomplete bladder emptying in men with enlarged prostate.
Benefits
- Effectively manages troublesome lower urinary tract symptoms
- Improves urine flow and bladder emptying
- Provides sustained action through modified-release formulation
- Enables convenient once-daily dosing
- May reduce the risk of acute urinary retention
- Generally well-tolerated by most patients
- Does not affect prostate size but improves symptoms
- May delay or prevent the need for prostate surgery in some cases
How It Works
Tamsulosin selectively blocks alpha-1A adrenergic receptors in the prostate, bladder neck, and urethra. This relaxes smooth muscles in these areas, reducing tension around the urethra and facilitating easier urine flow. The medication manages symptoms without shrinking the enlarged prostate.
Dosage
Patient Type | Standard Dosage | Timing |
---|---|---|
Adult men | 0.4mg once daily | 30 minutes after the same meal each day |
Swallow tablet whole without chewing or crushing to maintain the modified-release action. Dosage may be adjusted based on patient response.
Duration of Action
Contiflo OD begins working within 2-3 days, though full therapeutic effects may take 2-4 weeks to develop. The modified-release formulation provides symptom relief for 24 hours, enabling once-daily dosing. Effects last only while taking the medication.
Side Effects
Common side effects include dizziness, headache, runny or stuffy nose, and abnormal ejaculation. Most side effects are mild and often improve as the body adjusts to the medication. Less common effects include fatigue, drowsiness, and orthostatic hypotension.
Warning
Contiflo OD may cause dizziness, fainting, or vision changes, especially when starting treatment. Avoid driving or operating machinery if affected. Seek immediate medical attention for chest pain, priapism (prolonged erections lasting over 4 hours), or fainting spells.
Pregnancy and Breastfeeding
Contiflo OD is not indicated for use in women. It is specifically designed for men with benign prostatic hyperplasia.
Interaction
- May interact with other alpha-blockers, potentially causing low blood pressure
- Can interact with certain antihypertensive medications
- Possible interaction with strong CYP3A4 inhibitors, affecting tamsulosin metabolism
- May enhance blood pressure-lowering effects of PDE5 inhibitors
- Potential interaction with warfarin, requiring close monitoring
Precaution
Use with caution in patients with kidney or liver impairment. May cause Intraoperative Floppy Iris Syndrome during cataract surgery; inform eye surgeon about tamsulosin use. First dose may cause pronounced drop in blood pressure; take initial dose at bedtime. Do not discontinue abruptly without medical advice.
Important Information
Inform your doctor about any liver or kidney disease, planned eye surgery, history of low blood pressure, or use of other alpha-blockers before starting treatment. Take exactly as prescribed. Contiflo OD treats BPH symptoms but does not cure the underlying condition. Regular medical follow-up is necessary to monitor effectiveness and side effects.
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