Fleming Suspension 457 is an oral antibiotic combination containing Amoxicillin and Clavulanic Acid. This formulation is designed to provide broad-spectrum antibacterial coverage, particularly effective against beta-lactamase producing bacteria. The suspension form makes it suitable for pediatric use or for adults who have difficulty swallowing tablets.
Uses
Fleming Suspension 457 is primarily used to treat bacterial infections such as:
- Upper and lower respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Dental infections
- Otitis media (middle ear infections)
- Sinusitis
- Typhoid Fever
- Infections caused by beta-lactamase producing bacteria
Benefits
- Effective against a wide range of bacterial infections, including resistant strains
- Combination of Amoxicillin and Clavulanic Acid enhances efficacy
- Suitable for children and adults who cannot swallow tablets
- Broad-spectrum antibiotic activity
- Clavulanic Acid helps overcome certain types of antibiotic resistance
- Generally well-tolerated in most patients
How It Works
Amoxicillin works by inhibiting bacterial cell wall synthesis. Clavulanic Acid is a beta-lactamase inhibitor that prevents certain bacteria from inactivating Amoxicillin. This combination allows the antibiotic to be effective against a broader range of bacteria, including some resistant strains.
Dosage
Dosage varies based on age, weight, and the condition being treated. Typical dosages are calculated based on the Amoxicillin component. Always follow the prescribing physician’s instructions for dosage and duration of treatment.
Side Effects
Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Skin rash
- Candidiasis (oral thrush)
- Headache
Rare but serious side effects can include severe allergic reactions or liver problems.
Warning
This medication can cause serious allergic reactions, especially in patients with a history of penicillin allergy. If signs of an allergic reaction occur (rash, itching, swelling, severe dizziness, trouble breathing), seek immediate medical attention. Use with caution in patients with liver disease.
Interaction
Fleming Suspension may interact with several medications. Key interactions include:
- Oral contraceptives (reduced effectiveness)
- Allopurinol (increased risk of skin rash)
- Anticoagulants (increased risk of bleeding)
- Probenecid (increased amoxicillin levels)
- Methotrexate (increased methotrexate toxicity)
Always inform the prescribing physician about all medications being taken.
Important Information
Complete the full course of antibiotics as prescribed, even if symptoms improve. Shake the suspension well before each use. Measure doses accurately using the provided measuring device. Store in a cool, dry place and refrigerate if instructed. If symptoms persist or worsen, contact your healthcare provider. Overuse of antibiotics can lead to antibiotic resistance.
Reviews
There are no reviews yet.