Maldox Suspension 15ml (New Pack)

Maldox Suspension is a prescription medication containing two active ingredients: sulfadoxine and pyrimethamine. It belongs to the class of drugs known as antifolates and is primarily used for the treatment and prevention of specific types of malaria.

Uses

Maldox Suspension is indicated for the following:

1. Treatment of uncomplicated Plasmodium falciparum malaria: This medication is effective in treating malaria caused by the Plasmodium falciparum parasite, which is responsible for the most severe form of the disease.
2. Intermittent preventive treatment (IPT) of malaria during pregnancy: Maldox Suspension is used as a preventive measure to reduce the risk of malaria in pregnant women living in areas with high malaria transmission rates.

Benefits

• Effective in treating uncomplicated Plasmodium falciparum malaria
• Helps prevent malaria in pregnant women, reducing the risk of complications
• Convenient oral suspension formulation for ease of administration
• May be used as part of combination therapy for improved efficacy

Key Ingredients

The two active ingredients in Maldox Suspension are:

1. Sulfadoxine: A long-acting sulfonamide antibiotic that inhibits the synthesis of folic acid in the malaria parasite.
2. Pyrimethamine: An antifolate agent that also interferes with the synthesis of folic acid, preventing the growth and replication of the malaria parasite.

Mechanism of Action

Sulfadoxine and pyrimethamine work synergistically to disrupt the folate metabolism of the malaria parasite, thereby inhibiting its growth and replication. By blocking the synthesis of essential folate derivatives, these two agents prevent the parasite from multiplying and spreading within the host’s red blood cells.

Dosage and Administration

>2 months:
5-10 kg: One-half tablet orally one time
11-20 kg: 1 tablet orally one time
21-30 kg: 1.5 tablet orally one time
31-45 kg: 2 tablets orally one time
>45 kg: 3 tablets orally one time

The dosage of Maldox Suspension depends on the intended use (treatment or prevention) and the patient’s age, weight, and clinical condition. It is crucial to follow the instructions provided by a healthcare professional and complete the entire course of treatment as prescribed.

Side Effects

Maldox Suspension may cause side effects such as nausea, vomiting, diarrhea, abdominal pain, and skin rash. Rare but more severe side effects may include allergic reactions, bone marrow suppression, and liver or kidney dysfunction. If you experience any severe or persistent side effects, seek medical attention immediately.

Warnings and Precautions

Maldox Suspension should be used with caution in individuals with certain medical conditions, such as severe renal or hepatic impairment, folate deficiency, or a history of hypersensitivity to sulfonamides or pyrimethamine. It is important to inform your healthcare provider about any other medications you are taking, as drug interactions may occur.

Important Information

While Maldox Suspension is effective in treating and preventing malaria, it is crucial to follow appropriate preventive measures, such as using insect repellents, sleeping under insecticide-treated bed nets, and seeking prompt medical attention if malaria symptoms develop.