Methimez 5mg Tablet (Methimazole) x90

Methimez 5mg Tablet contains Methimazole, an antithyroid medication used to treat hyperthyroidism. This medication effectively reduces thyroid hormone production, helping control symptoms of overactive thyroid conditions including Graves’ disease and toxic multinodular goiter.

Uses

Methimez 5mg Tablet treats hyperthyroidism by reducing excessive thyroid hormone production. It’s prescribed for Graves’ disease, toxic multinodular goiter, and toxic adenoma. The medication helps prepare patients for thyroid surgery or radioactive iodine therapy when needed.

Benefits

• Effectively reduces thyroid hormone production
• Controls symptoms of hyperthyroidism quickly
• Reduces heart rate and blood pressure
• Improves weight gain and reduces tremors
• Helps normalize metabolic rate
• Reduces anxiety and nervousness
• Improves sleep quality and reduces sweating
• Prevents thyroid storm complications
• Suitable for long-term management

How It Works

Methimez works by inhibiting thyroid peroxidase, an enzyme essential for thyroid hormone synthesis. This blocks the formation of thyroid hormones (T3 and T4) in the thyroid gland, gradually reducing circulating hormone levels and alleviating hyperthyroid symptoms.

Dosage

Take Methimez with or without food at the same time each day. Divide doses evenly throughout the day for optimal control.

Duration of Action

Methimez begins working within hours but clinical improvement typically occurs within 2-4 weeks. Maximum therapeutic effects are usually seen after 6-8 weeks of consistent use. The medication has a half-life of 4-6 hours, requiring multiple daily doses for sustained effect.

Side Effects

Common side effects include skin rash, itching, headache, and mild gastrointestinal upset. Some patients experience joint pain, muscle aches, or temporary hair loss. Serious but rare side effects include severe liver problems, low white blood cell count, or agranulocytosis requiring immediate medical attention.

Warning

Methimez can cause serious liver damage and life-threatening blood disorders. Regular blood tests are essential to monitor liver function and blood cell counts. Discontinue immediately and seek medical attention for signs of infection, unusual bleeding, severe fatigue, or jaundice. Not suitable for treating thyroid storm emergencies.

Pregnancy and Breastfeeding

Methimez crosses the placenta and can affect fetal thyroid development. Use during pregnancy only when benefits clearly outweigh risks to the fetus. The medication passes into breast milk in small amounts. Breastfeeding mothers should be monitored closely along with their infants.

Interaction

• May enhance effects of anticoagulants like warfarin
• Possible interaction with beta-blockers affecting heart rate
• May alter effectiveness of certain diabetes medications
• Potential interaction with digoxin requiring dose adjustments
• Could affect response to certain vaccines
• May interact with theophylline, requiring monitoring

Precaution

Regular monitoring of liver function and blood counts is essential during treatment. Use cautiously in patients with liver disease or blood disorders. Inform all healthcare providers about Methimez use before any medical procedures. Avoid in patients with previous severe reactions to antithyroid medications.

Important Information

Methimez requires regular medical supervision and laboratory monitoring. Do not stop taking suddenly without medical advice as this can worsen hyperthyroidism. Store at room temperature away from moisture and heat. Carry identification indicating thyroid medication use. Report any signs of infection, unusual bleeding, or severe fatigue immediately to your healthcare provider.