Normoretic Tablet (Amiloride) x100

Normoretic is a combination medication containing Amiloride Hydrochloride (5mg) and Hydrochlorothiazide (50mg). This dual-action diuretic formulation is designed to manage hypertension, heart failure, and edema by promoting fluid elimination and electrolyte balance.

Uses

Normoretic is primarily used to:

• Treat high blood pressure (hypertension)
• Manage heart failure symptoms
• Reduce edema associated with various conditions
• Aid in the treatment of ascites due to liver cirrhosis

Benefits

• Effectively lowers blood pressure
• Reduces fluid retention and swelling
• Decreases strain on the cardiovascular system
• Helps alleviate symptoms of heart failure
• Potassium-sparing effect of Amiloride balances the potassium loss caused by Hydrochlorothiazide
• May reduce the risk of heart attacks and strokes in hypertensive patients
• Single tablet combining two medications for improved compliance

How It Works

Amiloride Hydrochloride inhibits sodium reabsorption in the distal tubules of the kidneys, while Hydrochlorothiazide increases the excretion of sodium, chloride, and water by inhibiting their reabsorption. This dual mechanism leads to increased urine production and reduced fluid volume in the body.

Dosage

The typical dosage is one tablet daily or as prescribed by a healthcare professional. Dosage may be adjusted based on individual patient response and medical condition. Always follow your doctor’s instructions.

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Headache
• Nausea or stomach upset
• Increased urination
• Electrolyte imbalances Serious side effects, though rare, may include severe dehydration or allergic reactions. Seek immediate medical attention if you experience symptoms like severe dizziness, fainting, or difficulty breathing.

Warning

Use Normoretic with caution in patients with kidney or liver disease, gout, or diabetes. Regular monitoring of electrolyte levels, particularly potassium, is essential. Avoid use in patients with anuria or hypersensitivity to sulfonamide-derived drugs.

Pregnancy and Breastfeeding

Normoretic is not recommended during pregnancy due to potential risks to the fetus. It should be used during breastfeeding only if the potential benefit justifies the potential risk to the infant.

Interaction

• May interact with other blood pressure medications
• Can affect the effectiveness of certain diabetes medications
• May increase lithium levels in the blood
• Potential interaction with NSAIDs and certain supplements

Important Information

Take Normoretic as prescribed, typically in the morning to avoid nighttime urination. Regular blood pressure monitoring and periodic blood tests are necessary to ensure safe and effective use. Maintain adequate hydration unless otherwise directed by your doctor. Inform your healthcare provider of all medications and supplements you’re taking. Do not stop taking Normoretic abruptly without consulting your doctor.