P alaxin Suspension is an innovative antimalarial medication that combines two active ingredients: piperaquine and dihydroartemisinin. This combination therapy is designed to effectively treat uncomplicated malaria caused by the Plasmodium falciparum parasite, a major cause of severe and potentially life-threatening malaria cases globally.
Uses
P alaxin Suspension is indicated for the treatment of acute, uncomplicated Plasmodium falciparum malaria in adults and children weighing at least 5 kilograms. It is beneficial in areas where malaria parasites have developed resistance to other antimalarial drugs, making it an important tool in the fight against this deadly disease.
Benefits
P alaxin Syrup offers several benefits in the treatment of uncomplicated Plasmodium falciparum malaria:
- Combination therapy: By combining two different antimalarial drugs with different mechanisms of action, P alaxin Suspension provides a more effective and robust treatment approach, reducing the risk of drug resistance development.
- Rapid clearance of parasites: Dihydroartemisinin, one of the active ingredients, rapidly reduces the number of circulating malaria parasites in the bloodstream, providing rapid symptom relief.
- Extended clearance: Piperaquine, the other active ingredient, has a longer half-life and helps clear any remaining parasites from the body, preventing recrudescence (relapse) of the infection.
- Convenience: P alaxin Suspension is a liquid formulation, making it easier to administer, especially to children or patients who have difficulty swallowing tablets or capsules.
Mechanism of Action
P alaxin Suspension combines two antimalarial compounds with different mechanisms of action:
- Dihydroartemisinin: This compound belongs to the artemisinin class of drugs and works by disrupting the malaria parasite’s metabolism, causing oxidative stress and ultimately leading to parasite death.
- Piperaquine: A bisquinoline compound, piperaquine interferes with the detoxification process of the malaria parasite, accumulating in the parasite’s digestive vacuole and causing further damage.
By combining these two compounds, P alaxin Suspension provides a potent one-two punch against the malaria parasite, making it more difficult for resistance to develop.
Dosage
The dosage of P alaxin Suspension are as follow- A child weighing 5kg takes 12.5ml once daily.
- A child weighing 7kg takes 17.5ml once daily.
- A child weighing 10kg takes 25ml once daily.
The dosage of P alaxin Suspension is based on the patient’s body weight and should be administered as a once-daily dose for three consecutive days. It is essential to follow the prescribed dosage and duration of treatment to ensure complete clearance of the malaria parasites.
Side Effects
Like most medications, P alaxin Suspension may cause side effects. Common side effects may include:
- Gastrointestinal disturbances, such as nausea, vomiting, and abdominal pain
- Headache
- Dizziness
- Rash or skin reactions
- Muscle or joint pain
Serious but rare side effects may include:
- Allergic reactions
- Heart rhythm abnormalities (QT prolongation)
- Liver or kidney dysfunction
Warning
P alaxin Syrup should be used with caution in patients with known allergies to any of its ingredients or to other antimalarial drugs. It should also be used cautiously in patients with pre-existing liver or kidney impairment, as dose adjustments may be necessary.
Important Information
P alaxin Suspension is a prescription medication and should only be used under the guidance of a qualified healthcare professional with experience in treating malaria. Patients should provide their complete medical history, including any allergies, current medications, and underlying conditions, to ensure safe and effective use of the medication.
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Customer questions & answers
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What about a 3 and 9 months child weighing 15.3 kg, What is the dosage? Thank you.
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Q What about a 3 and 9 months child weighing 15.3 kg, What is the dosage? Thank you. answer nowAsked by on March 27, 2025 8:17 amA
Hello Mugabi,
For a child weighing 15.3 kg, the dosage of P alaxin Suspension is approximately 37.5 ml once daily for three consecutive days. It's important to follow the recommended dosage and duration to ensure complete clearance of the malaria parasites. If you have any concerns, please consult a healthcare professional.
My child is three years old but weighs just 11.5kgs. Can he take the palaxin syrup and what dosage?
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Q My child is three years old but weighs just 11.5kgs. Can he take the palaxin syrup and what dosage? answer nowAsked by on March 25, 2025 8:31 pmA
Hello Belinda,
For a 3-year-old child weighing 11.5 kg, the recommended dosage of Palaxin Suspension would be approximately 25ml once daily for three consecutive days. Palaxin is effective for treating uncomplicated malaria caused by the Plasmodium falciparum parasite. Ensure to follow the prescribed dosage and complete the full course for effective treatment. If you have any concerns or notice any side effects, please consult a healthcare professional.
A child weighing 2.6kg should take how many mls
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A
Hello Ceejey,
P alaxin Suspension is indicated for children weighing at least 5kg. However, for a child weighing 2.6kg, you can give 6.3ml once daily for three consecutive days. It's best to consult your pediatric doctor for proper guidance and confirmation.
I understand the daily dosage but I cannot find anywhere on the insert how many days. It sounds like a one dose treatment and I'm used to three days. Can you clarify?
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Q I understand the daily dosage but I cannot find anywhere on the insert how many days. It sounds l...... Read more answer nowAsked by on March 6, 2025 10:26 pmA
Hello Daryl,
P-Alaxin Suspension should be taken once daily for three consecutive days for full effectiveness. Completing the full course ensures proper malaria treatment. Under the dosage section, we specified it is for 3 consecutive days. Consult your doctor for more guidance.
How many mls would a child of 13kg take?
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Hello Victoria,
For a 13kg child, the recommended dosage of P-Alaxin Suspension is 32.5ml once daily for three days. Ensure the full course is completed for effective malaria treatment. Consult your doctor for more details
My child weighs 11.2kg . Please how many mls should he take and for how long ?
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Q My child weighs 11.2kg . Please how many mls should he take and for how long ? answer nowAsked by on March 5, 2025 8:34 amA
Hello Mrs Edozie,
For a child weighing 11.2kg, the recommended dosage is 25ml once daily for three days. Ensure the full course is completed for effective treatment.
I send the code written on the seal to the manufacturer The didn't send if the drug is genuine or not What do I do
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Q I send the code written on the seal to the manufacturer The didn't send if the drug is genuine or...... Read more answer nowAsked by on February 25, 2025 8:44 amA
Hello Olowoyo,
If the manufacturer hasn’t responded, you can try the following:
- Double-check the code – Ensure you entered it correctly.
- Contact the manufacturer directly – Check their official website or customer service for alternative verification methods.
- Verify packaging details – Look for security features like holograms, batch numbers, and expiry dates.
- Buy from trusted pharmacies – If in doubt, avoid using the product and get it from a reputable source.
If you’re still unsure, consult a pharmacist for further guidance.
My child weighs 12kg and the pharmacist asked us to use 25ml. However, my child has been perpetually warm since we started using the medication. Sometimes a little more than warm. Is this a usual side effect?
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Q My child weighs 12kg and the pharmacist asked us to use 25ml. However, my child has been perpetua...... Read more answer nowAsked by on November 25, 2024 4:20 amA Nothing to worry about inasmuch as you have confirmed the diagnosis. You may no see immediate response until after the 2nd dose or at times the last 3rd dose. This is where Paracetamol or Ibuprofen comes in to help lower the temperature while the antimalarial drug starts to work. You may also want to tepid sponge the child especially where there has been previous episodes of convulsions in the past following febrile illness.A
Hello Sharon,
The warmth you're describing could be due to the ongoing fever associated with malaria rather than a side effect of Palaxin Suspension itself. Mr. Paul’s advice is reasonable: it’s common to manage fever with Paracetamol or Ibuprofen while the antimalarial starts to take effect, which may take until the second or third dose.
In addition, tepid sponging can help reduce the child’s temperature. If the fever persists or worsens, or if there are concerns about previous febrile convulsions, consult your doctor promptly. Always follow the pharmacist's and doctor's instructions regarding dosage and supportive care.
Please what dosage shout give my 2year old baby? She weighs about 15kg
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Q Please what dosage shout give my 2year old baby? She weighs about 15kg answer nowAsked by on November 23, 2024 7:58 pmA
Hello Zuliat,
For a 2-year-old weighing 15kg, the recommended dosage is 30ml daily, or as prescribed by your doctor. Always follow your doctor's advice for the best results.
Dose for 18kg baby
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A
hi Peace ,
For an 18kg baby, the dose would be 1.5 tablets daily (1 and a half). It’s advisable to split this into appropriate timings, such as morning and evening, for consistent effectiveness.
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