Tandak Injection (Ceftriaxone and Sulbactam)

Tandak Injection is a potent antibiotic combination comprising ceftriaxone and sulbactam, designed to combat a wide range of bacterial infections, including those caused by antibiotic-resistant strains. This powerful injectable medication offers a comprehensive solution for various severe and life-threatening infections.

Uses of Tandak Injection

Tandak Injection is used for the

• Treatment of respiratory tract infections
• Management of urinary tract infections
• Treatment of intra-abdominal infections
• Management of skin and soft tissue infections
• Treatment of bone and joint infections
• Management of meningitis

Benefit

• Broad-spectrum antibiotic activity against both gram-positive and gram-negative bacteria
• Highly effective against many drug-resistant bacterial strains
• Synergistic combination enhances the potency and efficacy of ceftriaxone
• Shows synergistic activity against many problematic pathogens
• Enhanced bactericidal activity
• Reduces antibiotic resistance development
• Less frequent dosing required
• Rapid clinical response in severe infections

How It Works

Ceftriaxone in Tandak inhibits bacterial cell wall synthesis while Sulbactam protects ceftriaxone from degradation by bacterial enzymes. This combination overcomes resistance mechanisms and maintains effectiveness against multiple pathogens.

Dosage

Duration of Action

Tandak Injection begins working within 1-2 hours with therapeutic levels maintained for 12-24 hours. Treatment typically lasts 5-14 days depending on infection severity and type.

Side Effects

Common side effects include injection site pain, gastrointestinal disturbances, headache, and dizziness. Rare effects include allergic reactions, blood disorders, and kidney problems.

Warning

Severe hypersensitivity reactions can occur, especially in patients allergic to beta-lactams. Prolonged use may cause superinfection. Monitor kidney and liver function during extended therapy.

Pregnancy and Breastfeeding

Use Tandak during pregnancy only when benefits outweigh risks. Small amounts are excreted in breast milk; consider temporary interruption of breastfeeding during treatment.

Interactions

• Increased bleeding risk with anticoagulants
• Potential kidney toxicity with aminoglycosides
• Possible antagonism with bacteriostatic antibiotics
• May interfere with glucose testing
• Avoid calcium-containing solutions within 48 hours

Precautions

Use with caution in patients with gastrointestinal disease, seizure disorders, or kidney/liver impairment. Adjust dosage for patients with combined renal and hepatic dysfunction.

Important Information

Complete the full prescribed course of Tandak Injection even if symptoms improve. Store properly and use reconstituted solutions within recommended timeframes. Report severe side effects immediately to your healthcare provider.