Zironem Injection contains meropenem trihydrate, a broad-spectrum antibiotic used to treat serious bacterial infections.
How Zironem Injection Works:
- Binds to penicillin-binding proteins to prevent bacterial cell wall synthesis
- Exhibits bactericidal activity against gram-positive and gram-negative aerobic and anaerobic pathogens
- Can be used alone or combined with other antibacterial drugs as needed
Dosage and Administration:
- Dosed 500mg-2g every 8 hours by intravenous infusion over 15-30 minutes
- The dose depends on the type/severity of infection, renal function, and body weight in pediatrics
- Treatment duration ranges from 5 days for uncomplicated infections to 2+ weeks for severe presentations
- Dose needs adjustment in renal impairment due to reduced drug elimination
Precautions:
Hypersensitivity reactions are possible; discontinue infusion if this occurs
- Seizures and CNS adverse events reported; use with caution in CNS disorders
- Can cause thrombocytopenia and coagulation deficiencies rarely
- Only use if expected benefits outweigh potential antibiotic risks
Under medical observation, meropenem injection combats invasive bacterial strains when standard antibiotics cannot. Dosing regimens must be individualized and monitored to ensure safety and efficacy.
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