Tiniflox is a combination antibiotic containing Tinidazole and Ofloxacin. This dual-action formula effectively treats bacterial and protozoal infections. Trusted by healthcare professionals for addressing various infections including gastrointestinal, urinary tract, and reproductive system infections.
Uses
Tiniflox is primarily used to treat mixed bacterial infections. It’s particularly effective for urinary tract infections, gastrointestinal infections, pelvic inflammatory disease, and certain sexually transmitted infections. The combination therapy provides broader antimicrobial coverage than single-agent treatments.
Benefits
- Treats both anaerobic and aerobic bacterial infections simultaneously
- Reduces treatment duration compared to sequential therapies
- Provides effective coverage against resistant microorganisms
- Decreases risk of recurrent infections
- Offers convenient dosing schedule for better compliance
- Demonstrates rapid symptom relief
- Prevents spread of infection to other body systems
How It Works
Tiniflox works through a dual mechanism of action. Ofloxacin inhibits bacterial DNA gyrase, preventing DNA replication and cell division in susceptible bacteria. Tinidazole is activated within microbial cells, damaging microbial DNA and inhibiting nucleic acid synthesis, effectively eliminating anaerobic bacteria and protozoa.
Duration of Action
Tiniflox begins working within 2-3 hours after administration. Ofloxacin reaches peak blood levels in 1-2 hours, while Tinidazole peaks at 2-3 hours. The antimicrobial action persists for 12-24 hours, allowing for convenient dosing. Complete treatment courses typically range from 5-10 days depending on infection type and severity.
Dosage
Patient Type | Standard Dosage | Severe Infections | Frequency |
---|---|---|---|
Adults | 1 tablet | 2 tablets | Every 12 hours |
Elderly | 1 tablet | 1 tablet | Every 12-24 hours |
Take with or without food. Complete the full prescribed course even if symptoms improve.
Side Effects
Common side effects include nausea, headache, dizziness, and metallic taste. Less common effects may include photosensitivity, tendon inflammation, and disturbances in taste or smell. Most side effects are mild and resolve upon completion of treatment.
Warning
Do not consume alcohol during and for at least 48 hours after completing Tiniflox treatment, as severe nausea, vomiting, and abdominal cramps may occur. Avoid excessive sun exposure. Discontinue and seek medical attention if severe allergic reactions, tendon pain, or severe diarrhea occurs.
Pregnancy and Breastfeeding
Tiniflox is contraindicated during pregnancy and breastfeeding. The combination may harm fetal development and pass into breast milk. Women who are pregnant or breastfeeding should inform their healthcare provider to discuss alternative treatment options.
Interaction
- May reduce effectiveness of oral contraceptives
- Increases risk of toxicity when taken with NSAIDs
- Can elevate blood levels of theophylline and caffeine
- May interact with blood thinners, increasing bleeding risk
- Decreases absorption when taken with antacids or iron supplements
Precaution
Patients with kidney or liver impairment may require dosage adjustment. Tiniflox may cause dizziness; avoid driving or operating machinery until effects are known. Stay adequately hydrated during treatment. Diabetic patients should monitor blood glucose carefully as Tiniflox may affect glucose levels.
Important Information
Complete the entire prescribed course of Tiniflox even if symptoms improve before completion. Take doses at evenly spaced intervals to maintain effective blood levels. If a dose is missed, take it as soon as remembered unless it’s almost time for the next dose. Never double dose to make up for a missed dose.
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