Amodiaquine Suspension is an antimalarial medication containing Amodiaquine Hydrochloride B.P., equivalent to 50 mg of amodiaquine base. This liquid formulation provides a targeted approach to managing malaria infections in various patient populations.
Uses
Amodiaquine Suspension is primarily indicated for the prevention and treatment of malaria, particularly in regions with chloroquine-resistant Plasmodium falciparum strains. It is an essential medication in comprehensive malaria management strategies.
Benefits
- Effective against specific malaria parasite strains
- Convenient liquid suspension for easy administration
- Suitable for children and adults
- Precise dosing with standardized concentration
- Rapid onset of antimalarial action
- Supports targeted malaria treatment protocols
How It Works
Amodiaquine interferes with the malaria parasite’s ability to metabolize hemoglobin. By accumulating in the parasite’s food vacuole, it disrupts the parasite’s internal processes, preventing the neutralization of toxic waste products and ultimately causing parasite death.
Dosage
| Age/Weight | Dosage | Frequency |
|---|---|---|
| 0-1 year (5-10 kg) | 2.5 ml | As prescribed |
| 1-3 years (11-20 kg) | 5 ml | As prescribed |
| 4-6 years (21-30 kg) | 7.5 ml | As prescribed |
| 7-10 years (31-45 kg) | 10 ml | As prescribed |
| >10 years (>45 kg) | 15 ml | As prescribed |
Always follow healthcare professional’s specific dosing instructions.
Duration of Action
The medication begins working within 1-2 hours of administration. Peak therapeutic levels are reached within 2-4 hours. Protective and treatment effects can persist for several weeks, depending on the specific malaria protocol and individual patient factors.
Side Effects
Common side effects may include mild gastrointestinal discomfort, temporary headache, slight dizziness, skin reactions, and potential changes in liver function.
Warning
Use with caution in patients with liver disorders, blood complications, or known hypersensitivity to amodiaquine. Regular monitoring of liver function and blood parameters is recommended during treatment.
Pregnancy and Breastfeeding
Consult healthcare provider before use during pregnancy or while breastfeeding. Potential risks and benefits must be carefully evaluated on an individual basis.
Interactions
- May interact with hepatotoxic medications
- Potential interference with some immunosuppressant drugs
- Can affect absorption of certain antibiotics
- Possible interactions with medications metabolized by liver enzymes
Precautions
Store at room temperature, protect from direct sunlight, keep out of children’s reach, do not exceed recommended dosage, and complete full course of treatment. Avoid alcohol consumption during treatment.
Important Information
Amodiaquine Suspension should be used under strict medical supervision. Regular liver function and blood tests are essential during treatment. If severe side effects or symptoms persist, consult healthcare professional immediately. Shake well before each use and use the provided measuring device for accurate dosing.
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