Duodart Capsule combines dutasteride and tamsulosin hydrochloride to treat benign prostatic hyperplasia (BPH). This dual-action medication alleviates symptoms, reduces prostate size, improves urinary flow, and lowers the risk of acute urinary retention and BPH-related surgery.
Uses
Duodart is used as combination therapy for treating moderate to severe symptoms of benign prostatic hyperplasia (BPH). It helps reduce the risk of acute urinary retention and the need for BPH-related surgery in patients with significant prostate enlargement symptoms.
Benefits
- Alleviates BPH symptoms effectively
- Reduces prostate size over time
- Improves urinary flow rate
- Lowers risk of acute urinary retention
- Decreases need for BPH-related surgery
- Provides dual-action treatment approach
- Offers comprehensive BPH management
How It Works
Duodart combines dutasteride and tamsulosin with complementary mechanisms. Dutasteride inhibits the 5-alpha-reductase enzyme, reducing dihydrotestosterone (DHT) levels and shrinking the prostate gland. Tamsulosin, an alpha-1 blocker, relaxes muscles in the prostate and bladder neck, improving urinary flow. This combination addresses both underlying prostate enlargement and provides immediate symptom relief.
Dosage
| Patient Group | Standard Dosage | Administration |
|---|---|---|
| Adult Men | 1 capsule daily | With or without food |
| Elderly | 1 capsule daily | Same as adults |
Take Duodart at the same time each day for optimal effectiveness. Swallow capsules whole with water.
Duration of Action
Duodart begins working within days, with tamsulosin providing rapid symptom relief within 1-2 weeks. Dutasteride’s effects on prostate size reduction become apparent after 3-6 months of treatment. Maximum benefits typically occur after 6-12 months of continuous therapy. Long-term use maintains symptom control and prevents BPH progression.
Side Effects
Common side effects include decreased sexual function, ejaculation problems, dizziness, headache, stuffy nose, rash, and fatigue. Gastrointestinal issues such as diarrhea, nausea, and vomiting may also occur. Most side effects are mild and diminish over time with continued treatment.
Warning
Duodart Capsule is not suitable for everyone. It should not be taken by people allergic to its ingredients, individuals with severe liver problems, women, and children. The medication may cause dizziness and fainting, especially when standing up quickly. Consult your doctor before use if you have heart problems, blood clots, or known allergies.
Pregnancy and Breastfeeding
Duodart Capsule is contraindicated for women, especially those who are or may become pregnant. Women should not handle crushed or broken capsules due to potential absorption through skin and risk to male fetuses. This medication is exclusively indicated for men with BPH and has no use in women or children.
Interaction
- May interact with blood thinners, increasing bleeding risk
- Possible enhanced effects with heart medications
- Potential interactions with high blood pressure medications
- May interact with certain depression medications
- Possible effects when combined with allergy medications
Precaution
Regular monitoring by healthcare provider is essential. Inform doctors about Duodart use before any medical procedures. The medication affects PSA test results, potentially masking prostate cancer detection. Use caution when driving or operating machinery due to possible dizziness. Store at room temperature away from moisture and heat.
Important Information
This medication is available only by prescription. It may affect PSA test results, so inform your doctor if you’re having a PSA test. Women who are or may become pregnant should not handle this capsules due to potential risks to male fetuses. Discuss alternative treatments with your doctor if this is not suitable for you. Regular follow-ups with your healthcare provider are essential to monitor your response to treatment and manage any potential side effects.
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