Glucophage 500mg Tablet is a prescription medication containing metformin hydrochloride as its active ingredient. It belongs to the biguanide class of drugs and is primarily used to manage type 2 diabetes mellitus. Glucophage works by improving insulin sensitivity and reducing glucose production in the liver, helping to control blood sugar levels effectively.
Uses
Glucophage 500mg Tablet is primarily used to treat type 2 diabetes in adults and children over 10 years old. It’s often prescribed as a first-line treatment, either alone or in combination with other diabetes medications. In some cases, it may also be used to treat polycystic ovary syndrome (PCOS) or to prevent diabetes in high-risk individuals.
Benefits
- Effectively lowers blood glucose levels
- May promote modest weight loss
- Improves insulin sensitivity
- Reduces the risk of diabetes-related complications
- Does not typically cause hypoglycemia when used alone
- May have cardiovascular benefits
- Potential anti-cancer properties (under investigation)
- Cost-effective treatment option
How It Works
Metformin works by decreasing glucose production in the liver, reducing glucose absorption in the intestines, and improving insulin sensitivity in body tissues. This multi-faceted approach helps lower blood sugar levels without causing hypoglycemia. It also enhances the body’s response to naturally produced insulin.
Dosage
The typical starting dose of Glucophage is 500mg twice daily or 850mg once daily, taken with meals. The dosage may be gradually increased based on blood glucose levels and tolerance. The maximum recommended daily dose is 2550mg for adults. Always follow your doctor’s prescription and do not alter the dosage without medical advice.
Side Effects
Common side effects of Glucophage 500mg Tablet may include nausea, diarrhea, stomach upset, and a metallic taste in the mouth. These often improve over time. Serious side effects are rare but can include lactic acidosis, especially in people with kidney problems. Contact your doctor immediately if you experience severe stomach pain, muscle pain, or difficulty breathing.
Warning
Glucophage 500mg Tablet should not be used by individuals with severe kidney disease, liver disease, or conditions that may cause lactic acidosis. It should be temporarily discontinued before surgery or certain imaging procedures using iodinated contrast. Alcohol should be avoided while taking this medication.
Pregnancy and Breastfeeding
Pregnant women should discuss the risks and benefits of Glucophage with their healthcare provider. It may be used during pregnancy if clearly needed. Metformin does pass into breast milk, so breastfeeding mothers should consult their doctor before use.
Interaction
- May interact with certain diabetes medications, potentially increasing the risk of hypoglycemia
- Can interact with some heart and blood pressure medications
- May affect the absorption of vitamin B12
- Interactions possible with certain contrast dyes used in medical imaging
- Could interact with alcohol, increasing the risk of lactic acidosis
Important Information
Regular monitoring of blood glucose levels and kidney function is essential while taking Glucophage. Maintain a healthy diet and exercise regimen as part of your diabetes management plan. Inform your healthcare provider about all medications you’re taking to avoid potential interactions. If you experience symptoms of lactic acidosis, such as weakness, unusual muscle pain, difficulty breathing, or stomach discomfort, seek immediate medical attention.
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