Insulatard 100 is an intermediate-acting NPH (Neutral Protamine Hagedorn) human insulin suspension. This cloudy insulin preparation contains 100 IU/mL of isophane insulin, providing extended blood glucose control for patients with diabetes mellitus. It’s designed to maintain consistent basal insulin levels throughout the day.
Uses
Insulatard is prescribed for blood glucose management in patients with type 1 and type 2 diabetes mellitus. It’s particularly effective for providing background insulin coverage and maintaining stable blood sugar levels between meals and overnight.
Benefits
- Provides stable basal insulin coverage
- Offers intermediate-duration glucose control
- Reduces nighttime hypoglycemia risk
- Helps maintain consistent fasting glucose
- Cost-effective diabetes management
- Suitable for once or twice daily dosing
- Well-established safety profile
- Flexible timing options
How It Works
Insulatard’s isophane insulin crystals slowly dissolve after injection, providing a gradual release of insulin into the bloodstream. This controlled release helps maintain steady blood glucose levels over an extended period, making it effective for basal insulin coverage.
Dosage
| Time of Day | Initial Dose | Adjustment Period |
|---|---|---|
| Morning Dose | Individualized based on needs | Adjust every 2-3 days |
| Evening Dose | As prescribed by physician | Monitor fasting glucose |
Duration of Action
Onset begins within 1-2 hours after injection, with peak effect occurring between 4-12 hours. The duration of action typically lasts 18-24 hours. Individual response may vary based on factors such as injection site and physical activity.
Side Effects
Common side effects include injection site reactions, hypoglycemia, and weight gain. More serious side effects may include severe hypoglycemia, allergic reactions, or lipodystrophy. Monitor blood glucose regularly and report concerning symptoms to healthcare provider.
Warning
Risk of severe hypoglycemia if dosage is miscalculated. Never share insulin devices. Must be gently mixed before use – do not shake vigorously. Seek immediate medical attention for severe hypoglycemia or allergic reactions.
Pregnancy and Breastfeeding
Insulatard can be used during pregnancy and breastfeeding under medical supervision. Insulin requirements often change during pregnancy, requiring careful monitoring and dose adjustments.
Interactions
- Beta-blockers may mask hypoglycemia symptoms
- Corticosteroids can increase insulin requirements
- ACE inhibitors may enhance insulin sensitivity
- Alcohol may intensify hypoglycemic effects
- Some antibiotics may affect glucose control
Precautions
Regular blood glucose monitoring is essential. Rotate injection sites to prevent lipodystrophy. Keep glucose tablets or sugar source readily available. Adjust doses for exercise, illness, or significant diet changes. Store unopened vials in refrigerator and in-use vials at room temperature.
Important Information
Inspect Insulatard before each use – it should appear uniformly cloudy after gentle mixing. Never freeze or expose to extreme heat. Carry medical identification indicating diabetes and insulin use. Maintain consistent meal timing and daily routines for optimal glucose control. Regular medical check-ups are essential for dose adjustments and monitoring treatment effectiveness with Insulatard.
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