Laritin Tablet 20mg/120mg (Dispersible) x12

Laritin Tablet 20mg/120mg (Dispersible) is a fixed-dose combination antimalarial medication containing artemether and lumefantrine. This child-friendly dispersible formulation offers effective treatment of malaria caused by Plasmodium falciparum, including multi-drug resistant strains.

Uses

Laritin Tablet 20mg/120mg is used for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum in children. It is effective against chloroquine-resistant strains and is recommended as first-line treatment in many malaria-endemic regions according to WHO guidelines.

Benefits

• Highly effective against Plasmodium falciparum malaria
• Works against drug-resistant malaria strains
• Child-friendly dispersible formulation
• Rapid parasite clearance
• Reduces risk of recurrence
• Convenient twice-daily dosing
• Easy to administer dispersible tablet
• Internationally recognized first-line treatment

How It Works

Laritin Tablet works through a dual-action mechanism. Artemether rapidly reduces parasite load by interfering with parasite transport proteins, while lumefantrine has a longer half-life and eliminates remaining parasites. This combination effectively breaks the malaria life cycle in the blood.

Duration of Action

Artemether provides rapid action within hours of administration with a half-life of 2-3 hours. Lumefantrine acts more slowly with a half-life of 3-6 days, providing extended protection against recurrent infection.

Dosage

Warnings

Do not use in children with severe malaria requiring parenteral treatment. Avoid in patients with known hypersensitivity to artemether or lumefantrine. This medication may prolong QT interval, so use with caution in children with cardiac conditions. Complete the full course of treatment even if symptoms improve.

Side Effects

Common side effects include headache, dizziness, abdominal pain, loss of appetite, nausea, weakness, joint pain, muscle pain, and mild sleep disturbances. Most side effects are mild and transient.

Pregnancy and Breastfeeding

Not applicable for this pediatric formulation. For adolescent girls of childbearing age, consult healthcare provider before administration.

Interactions

• Antiarrhythmic drugs (increased risk of QT prolongation)
• Antipsychotics (increased risk of QT prolongation)
• CYP3A4 inhibitors (increased drug levels)
• CYP3A4 inducers (decreased effectiveness)
• Antiretroviral drugs (potential altered efficacy)
• Grapefruit juice (may increase drug concentration)

Precautions

Dispersible tablets should be dissolved in a small amount of water before administration. Give with food or milk to increase absorption, particularly fatty foods if possible. Monitor child for 1 hour after dosing; if vomiting occurs within 1 hour, repeat the dose. Ensure adequate hydration throughout treatment.

Important Information

Laritin Tablet 20mg/120mg must be taken for the full 3-day course to ensure complete parasite clearance. If fever persists after treatment completion, seek medical attention promptly. Store tablets in the original packaging at room temperature, protected from light and moisture.