Metoprolol Tartrate 100mg Tablet is a selective beta-1 adrenergic receptor blocker used to treat high blood pressure, chest pain, and heart rhythm disorders. This medication helps reduce heart rate and blood pressure while improving heart function.
Uses
Metoprolol Tartrate treats hypertension, angina pectoris, and certain heart rhythm abnormalities. It’s prescribed for heart attack survivors to prevent future cardiac events and for heart failure management. Metoprolol also helps control symptoms of hyperthyroidism and prevents migraine headaches.
Benefits
- Effectively lowers high blood pressure
- Reduces frequency and severity of chest pain episodes
- Decreases risk of heart attack and stroke
- Improves heart function in heart failure patients
- Controls irregular heart rhythms
- Reduces migraine frequency
- Protects heart muscle after heart attack
- Improves exercise tolerance in heart conditions
- Helps manage hyperthyroid symptoms
How It Works
Metoprolol Tartrate selectively blocks beta-1 receptors in the heart, reducing the effects of adrenaline and noradrenaline. This action decreases heart rate, reduces force of heart contractions, and lowers blood pressure. The medication also reduces the heart’s oxygen demand, making it beneficial for angina and post-heart attack care.
Dosage
Condition | Starting Dose | Maximum Daily Dose |
---|---|---|
Hypertension | 50-100mg twice daily | 400mg daily |
Angina | 50mg twice daily | 400mg daily |
Heart Attack | 25-50mg twice daily | 200mg daily |
Take Metoprolol with or immediately after meals. Divide daily dose into two or three smaller doses for better tolerance.
Duration of Action
Metoprolol Tartrate begins working within 1-2 hours of administration. Peak effects occur at 1-2 hours and last for 6-12 hours. Blood pressure reduction may take several weeks to reach maximum benefit. Regular dosing maintains consistent cardiovascular protection throughout the day.
Side Effects
Common side effects include fatigue, dizziness, slow heart rate, and cold hands or feet. Some patients experience nausea, depression, or sleep disturbances. Serious side effects include severe bradycardia, heart block, worsening heart failure, or bronchospasm in susceptible individuals.
Warning
Never stop Metoprolol suddenly as this can cause dangerous rebound hypertension or heart problems. Gradual dose reduction over 1-2 weeks is necessary. Use caution in patients with asthma, COPD, diabetes, or peripheral vascular disease. Monitor heart rate and blood pressure regularly during treatment.
Pregnancy and Breastfeeding
Metoprolol crosses the placenta and may cause fetal bradycardia, low birth weight, or other complications. Use only if benefits clearly outweigh risks. The medication passes into breast milk but is generally considered compatible with breastfeeding under medical supervision.
Interaction
- May mask hypoglycemia symptoms when used with diabetes medications
- Increased risk of heart block with calcium channel blockers
- Enhanced blood pressure lowering with other antihypertensives
- Possible interaction with certain antidepressants
- May reduce effectiveness of bronchodilators in asthma patients
- Alcohol may enhance blood pressure lowering effects
Precaution
Use cautiously in patients with heart failure, diabetes, kidney or liver disease, and respiratory conditions. Regular monitoring of heart rate, blood pressure, and kidney function is essential. Inform surgeons about Metoprolol use before procedures. Avoid abrupt discontinuation even when switching medications.
Important Information
Metoprolol requires regular medical monitoring and dosage adjustments. Check blood pressure and heart rate regularly at home if recommended. Maintain consistent dosing schedule for optimal effectiveness. Store at room temperature away from moisture and heat. Report any unusual symptoms, especially slow heart rate, dizziness, or breathing difficulties to your healthcare provider immediately.
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