Zinnat Tablets 250mg contain the active ingredient Cefuroxime, a powerful second-generation cephalosporin antibiotic. This formulation offers a convenient and effective way to combat various bacterial infections in both adults and children.
Uses
- Treatment of respiratory tract infections (e.g., bronchitis, pneumonia)
- Management of urinary tract infections
- Treatment of skin and soft tissue infections
- Prophylaxis for surgical procedures
- Suitable for use in adults and children (as per dosage guidelines)
- Treatment of ear infections (otitis media)
- Sinusitis
- Skin and soft tissue infections
- Lyme disease
- Treatment of Typhoid Fever
Benefits
- Broad-spectrum antibiotic effective against a wide range of bacteria
- Convenient oral tablet formulation for easy administration
- Reaches therapeutic levels in the body quickly for prompt relief
- It can be used as an alternative for patients with penicillin allergies
- Proven efficacy and safety profile when used as directed
How It Works
Cefuroxime works by interfering with bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs), disrupting the cross-linking of peptidoglycan, an essential component of bacterial cell walls. This leads to cell wall instability and eventual bacterial cell death. Its beta-lactamase stability provides effectiveness against many resistant strains.
Duration of Action
Zinnat begins antibacterial activity within 1-2 hours after administration. Peak blood levels occur 2-3 hours post-dose. The medication maintains therapeutic concentrations for approximately 12 hours, allowing twice-daily dosing. Clinical improvement typically begins within 48-72 hours of treatment initiation.
Dosage
Zinnat 250mg Dosage Guidelines
Adults and Adolescents (12 years and older)
| Infection Type | Dosage | Frequency |
|---|---|---|
| Standard infections | 250 mg (1 tablet) | Twice daily |
| Severe infections | 500 mg (2 tablets) | Twice daily |
| Urinary tract infections | 250 mg (1 tablet) | Twice daily |
| Lower respiratory tract infections (e.g., bronchitis) | 250-500 mg (1-2 tablets) | Twice daily |
| Sinusitis | 250-500 mg (1-2 tablets) | Twice daily |
| Gonorrhea | 1 g (4 tablets) | Single dose |
The dosage of Zinnat Tablets 250mg depends on the age, weight, and condition being treated. Always follow the dosage instructions provided by your healthcare provider or as specified on the product label.
Side Effects
Common side effects may include diarrhea, nausea, vomiting, and abdominal discomfort. Rare but more serious side effects can include allergic reactions, headaches, dizziness, and changes in liver function. Inform your healthcare provider immediately if you experience any concerning symptoms.
Warning
Zinnat Tablets should be used with caution in individuals with renal impairment, as dosage adjustments may be necessary. It should not be taken by individuals with known hypersensitivity to cefuroxime or other cephalosporin antibiotics. Inform your healthcare provider about any allergies or medical conditions before starting treatment.
Pregnancy and Breastfeeding
Zinnat is generally considered safe during pregnancy (Category B) but should be used only when clearly needed. It passes into breast milk in small amounts. Nursing mothers should monitor their infants for diarrhea, candidiasis, or allergic reactions. Consult healthcare provider before use during pregnancy or breastfeeding.
Interaction
- May decrease effectiveness of oral contraceptives
- Potential interaction with probenecid
- Can affect laboratory test results
- May interact with blood thinners
- Could affect kidney function tests
Precaution
Take Zinnat with food to improve absorption and reduce stomach upset. Maintain adequate hydration during treatment. Patients with kidney impairment may require dose adjustment. Be alert for signs of secondary infections or allergic reactions. Those with a history of gastrointestinal disease should use with caution.
Important Information
Complete the entire course of Zinnat Tablets as prescribed, even if symptoms improve, to prevent the development of antibiotic resistance. Do not share this medication with others, as inappropriate use can lead to antibiotic resistance. Store Zinnat Tablets as directed, away from direct sunlight and moisture.
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