Prizilcide Tablet (Praziquantel) x10

Prizilcide Tablet contains praziquantel 600mg, a broad-spectrum anthelmintic medication used to treat various parasitic worm infections. This medication is effective against several species of trematodes (flukes) and cestodes (tapeworms). Prizilcide offers a potent treatment option for parasitic infections, helping to eliminate worms and alleviate associated symptoms.

Uses

Prizilcide is primarily used to treat infections caused by:

• Schistosomiasis (bilharzia)
• Liver flukes (Clonorchis and Opisthorchis)
• Intestinal flukes (Fasciolopsis buski)
• Tapeworms (Taenia species)
• Neurocysticercosis in some cases

Benefits

• Effective against a wide range of parasitic worms
• Single-dose treatment for many infections
• Rapid action against parasites
• Generally well-tolerated
• Can be used in mass treatment programs for endemic areas

How It Works

Praziquantel, the active ingredient in Prizilcide, works by increasing the permeability of the parasite’s cell membrane to calcium ions. This leads to intense contractions and paralysis of the parasite’s muscles. The paralyzed parasites detach from the host tissues and are expelled from the body. Praziquantel also makes the parasites more vulnerable to the host’s immune system.

Dosage

The dosage of Prizilcide varies depending on the type of infection:

• For schistosomiasis: Usually a single dose of 40-60 mg/kg body weight
• For tapeworm infections: Typically 5-10 mg/kg as a single dose
• For liver and intestinal flukes: Often 25 mg/kg three times in one day Always follow your healthcare provider’s instructions regarding dosage and administration.

Side Effects

Common side effects may include abdominal pain, nausea, vomiting, diarrhea, headache, and dizziness. These are usually mild and transient. Rarely, more serious side effects can occur, including allergic reactions or neurological symptoms in cases of neurocysticercosis. If you experience severe side effects, seek medical attention immediately.

Warning

Prizilcide Tablet should be used with caution in patients with liver disease or heart conditions. It may cause dizziness and affect the ability to drive or operate machinery. In cases of neurocysticercosis, treatment may cause neurological symptoms due to the inflammatory response to dying parasites. Close medical supervision is required in such cases.

Pregnancy and Breastfeeding

Use during pregnancy should be carefully evaluated, weighing potential benefits against risks. Consult healthcare provider regarding breastfeeding, as praziquantel is known to be excreted in breast milk.

Interactions

• Chloroquine (may decrease the bioavailability of praziquantel)
• Carbamazepine and phenytoin (may decrease praziquantel levels)
• Cimetidine (may increase praziquantel levels)
• Rifampicin (may decrease praziquantel effectiveness)

Precautions

Take tablets whole with food and water. Regular monitoring may be required during treatment. Avoid alcohol consumption. Complete the prescribed course even if symptoms improve. Follow-up examinations may be necessary to confirm cure.

Important Information

Take Prizilcide with food. Crushing or chewing the tablets may increase absorption and side effects. Complete the full course of treatment as prescribed. Follow-up stool examinations may be necessary to confirm cure. In endemic areas, reinfection may occur, requiring repeat treatments. Inform your healthcare provider of all medications you’re taking. Seek medical attention if symptoms persist or worsen after treatment.