Pulmocef 500mg Tablet is an advanced cephalosporin antibiotic medication containing Cefuroxime. This broad-spectrum antibiotic effectively eliminates susceptible bacteria causing infections in multiple body systems.
Uses
Pulmocef 500mg Tablet treats respiratory tract infections including pharyngitis, tonsillitis, bronchitis, and pneumonia. It also treats urinary tract infections, skin infections, gonorrhea, meningitis, and serves as surgical prophylaxis to prevent post-operative infections.
Benefits
- Broad-spectrum antibacterial activity
- Effective against many gram-positive and gram-negative bacteria
- Resistant to many beta-lactamase enzymes
- High tissue penetration
- Good safety profile
- Convenient twice-daily dosing
- Suitable for various infection types
- Lower risk of certain side effects compared to first-generation cephalosporins
How It Works
Pulmocef works by binding to specific proteins in bacterial cell walls called penicillin-binding proteins. This inhibits the final stage of bacterial cell wall synthesis, weakening the cell wall and causing bacterial cell death through osmotic lysis.
Duration of Action
Pulmocef reaches peak plasma concentrations within 2-3 hours after oral administration. The elimination half-life is approximately 1.5 hours, and the drug remains active for 12 hours, enabling twice-daily dosing.
Dosage
Infection Type | Recommended Dosage | Frequency |
---|---|---|
Mild to moderate | 250mg | Every 12 hours |
Severe infections | 500mg | Every 12 hours |
Complicated UTI | 250mg | Every 12 hours |
Gonorrhea | 1000mg | Single dose |
Warnings
Discontinue use and seek immediate medical attention if signs of allergic reaction occur, including rash, itching, swelling, severe dizziness, or trouble breathing. Take the full prescribed course even if symptoms improve before completion.
Side Effects
Common side effects include diarrhea, nausea, vomiting, stomach pain, headache, and temporary changes in taste. Serious but rare side effects include severe allergic reactions, Clostridium difficile-associated diarrhea, blood disorders, and kidney problems.
Pregnancy and Breastfeeding
Pulmocef 500mg is generally considered safe during pregnancy when clearly needed. It passes into breast milk in small amounts. Consult healthcare providers before use during pregnancy or while breastfeeding.
Interactions
- Probenecid (increases Cefuroxime levels)
- Antacids and H2 blockers (reduce absorption)
- Oral contraceptives (may reduce effectiveness)
- Anticoagulants (increased bleeding risk)
- Nephrotoxic drugs (increased kidney damage risk)
- Bacteriostatic antibiotics (may interfere with bactericidal activity)
Precautions
Take Pulmocef with food to enhance absorption and reduce stomach upset. Complete the full course of antibiotics even if feeling better. Inform your doctor about kidney problems, previous allergic reactions to antibiotics, or digestive conditions.
Important Information
Pulmocef 500mg Tablet belongs to the cephalosporin group of antibiotics. It should be used only for bacterial infections, not viral infections like colds or flu. Overuse may lead to decreased effectiveness and antibiotic resistance, making future infections harder to treat. Pulmocef is a prescription-only antibiotic. Take at evenly spaced intervals to maintain blood levels. Complete the entire course even if feeling better to prevent bacterial resistance. Do not share with others or save for future illness. Keep well hydrated during treatment. Report persistent fever, new symptoms, or worsening condition to healthcare provider immediately.
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