Accord Levothyroxine 100mcg is a synthetic thyroid hormone replacement containing 100 micrograms of levothyroxine sodium. This prescription medication replaces or supplements the natural thyroid hormone (T4) in patients with thyroid hormone deficiency.
Uses
Accord Levothyroxine treats hypothyroidism (underactive thyroid) caused by thyroid gland removal, radiation treatment, natural hormone deficiency, or thyroid suppression therapy. It’s also used to manage thyroid cancer and to test for thyroid disorders. The 100mcg strength is appropriate for precise dosing based on individual needs.
Benefits
- Restores normal thyroid hormone levels
- Relieves symptoms of hypothyroidism
- Improves energy and reduces fatigue
- Enhances metabolism and weight management
- Normalizes body temperature regulation
- Improves cardiovascular function
- Supports healthy brain function and mood
- Promotes proper growth and development in children
- Prevents complications of untreated hypothyroidism
How It Works
Levothyroxine (T4) is converted in the body to the active form triiodothyronine (T3). These thyroid hormones regulate metabolism in most tissues by controlling protein synthesis and increasing oxygen consumption in cells. Accord Levothyroxine 100mcg provides a consistent daily dose of hormone to maintain stable thyroid function.
Dosage
| Patient Type | Starting Dosage | Typical Maintenance |
|---|---|---|
| Adults | 25-50mcg daily | 75-200mcg daily |
| Elderly | 12.5-25mcg daily | 50-125mcg daily |
Take Accord Levothyroxine on an empty stomach, 30-60 minutes before breakfast. Take at the same time each day for consistent blood levels. Dosage adjustments based on lab tests and clinical response.
Duration of Action
Accord Levothyroxine begins working within hours but takes 1-3 weeks for initial symptomatic improvement. The full therapeutic effect may require 4-8 weeks. Its half-life of 6-7 days allows stable blood levels with once-daily dosing. Thyroid function tests typically stabilize after 6-8 weeks of consistent treatment.
Side Effects
Most side effects indicate dose adjustment needs rather than true adverse reactions. Symptoms of excessive dose may include rapid heartbeat, anxiety, tremors, headache, insomnia, or weight loss. Rare allergic reactions may occur to inactive ingredients. Side effects typically resolve with dosage adjustment.
Warning
Do not use to treat obesity or for weight loss. Excessive doses can cause serious heart problems, bone loss, or thyroid crisis. Never adjust your dose without medical supervision. Thyroid hormone replacement is a lifelong treatment for most patients with hypothyroidism. Abrupt discontinuation can cause serious health consequences.
Pregnancy and Breastfeeding
Levothyroxine can be used during pregnancy and is often essential for maternal and fetal health. Dosage requirements may increase during pregnancy. Breastfeeding is compatible with levothyroxine treatment, as minimal amounts pass into breast milk. Regular monitoring during pregnancy is important.
Interaction
- Reduced absorption when taken with calcium or iron supplements
- Decreased effectiveness with certain antacids and acid reducers
- May affect blood glucose control in diabetic patients
- Possible increased effects when used with certain antidepressants
- Cholesterol-lowering resins can decrease absorption
Precaution
Patients with cardiovascular disease, adrenal insufficiency, or diabetes require careful monitoring when starting therapy. Elderly patients and those with longstanding hypothyroidism need gradual dose titration. Inform all healthcare providers about levothyroxine use before procedures or starting new medications.
Important Information
Accord Levothyroxine 100mcg is not interchangeable with other brands without medical supervision due to slight variations in bioavailability. Regular thyroid function tests are necessary to ensure proper dosing. Store at room temperature away from light and moisture. Take missed doses as soon as remembered unless close to next dose time.
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