DonyArt Plus 80/480 Tablets x6

DonyArt Plus 80/480 is a powerful antimalarial medication combining Artemether (80mg) and Lumefantrine (480mg). This fixed-dose artemisinin-based combination therapy (ACT) effectively treats acute, uncomplicated malaria caused by Plasmodium falciparum. It’s designed for rapid action against malaria parasites, offering a high cure rate with good tolerability.

Uses

DonyArt Plus 80/480 is primarily used for the treatment of acute, uncomplicated malaria in adults and children weighing 35 kg or more. It’s particularly effective against Plasmodium falciparum, including multidrug-resistant strains.

Benefits

• Rapid clearance of malaria parasites
• High cure rates for P. falciparum malaria
• Effective against multidrug-resistant strains
• Reduces risk of progression to severe malaria
• Well-tolerated by most patients
• Convenient fixed-dose combination

How It Works

Artemether rapidly reduces parasite numbers, while Lumefantrine eliminates residual parasites. This dual action ensures effective clearance of the infection and reduces the risk of parasite resistance developing.

Dosage

A total of 6 doses over 3 days is recommended for adults and children weighing 35 kg or more. Take 1 tablet as a single dose at 0, 8, 24, 36, 48, and 60 hours. Always complete the full course as directed by your healthcare provider.

Side Effects

Common side effects may include headache, dizziness, loss of appetite, nausea, vomiting, abdominal pain, and fatigue. Most side effects are mild and resolve without intervention.

Warning

Do not use in patients with severe malaria or a history of allergic reactions to the ingredients. Not recommended during the first trimester of pregnancy unless potential benefits outweigh risks.

Interaction

• Avoid concomitant use with drugs that prolong QT interval
• May interact with CYP3A4 inhibitors, potentially increasing Lumefantrine levels
• Use caution with drugs metabolized by CYP2D6
• Grapefruit juice may increase Lumefantrine levels
• Caution is advised when used with antiretroviral medications

Important Information

Take DonyArt Plus 80/480 with food or milk to enhance absorption. Complete the full course of treatment even if symptoms improve quickly. If vomiting occurs within 1 hour of dosing, repeat the dose. Seek immediate medical attention if symptoms worsen or persist after treatment.