Forxiga 5mg Tablet contains Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor. This medication helps control blood sugar levels in type 2 diabetes by preventing glucose reabsorption in the kidneys, allowing excess glucose to be eliminated through urine.
Uses
Forxiga 5mg Tablet treats type 2 diabetes mellitus as monotherapy or combination therapy. It’s also prescribed for heart failure with reduced ejection fraction and chronic kidney disease in diabetic patients. Forxiga helps improve glycemic control when diet and exercise alone are insufficient.
Benefits
- Effectively lowers blood glucose levels
- Promotes weight loss through glucose elimination
- Reduces blood pressure naturally
- Decreases risk of cardiovascular events
- Provides kidney protection in diabetic patients
- Lowers risk of heart failure hospitalization
- Does not cause hypoglycemia when used alone
- Offers once-daily convenient dosing
- Improves overall diabetes management
How It Works
Dapagliflozin blocks SGLT2 receptors in the kidney tubules, preventing glucose reabsorption from urine back into the bloodstream. This mechanism allows excess glucose to be eliminated through urination, reducing blood sugar levels without depending on insulin. The process also results in modest weight loss and blood pressure reduction.
Dosage
Patient Type | Starting Dosage | Maximum Dosage |
---|---|---|
Adults | 5mg once daily | 10mg once daily |
Elderly | 5mg once daily | 5mg once daily |
Take Forxiga at the same time each day, with or without food. Swallow the tablet whole with water.
Duration of Action
Forxiga 5mg begins working within hours of administration, with peak glucose-lowering effects occurring within 1-2 weeks of regular use. The medication’s effects last 24 hours per dose. Maximum therapeutic benefits are typically achieved after 4-6 weeks of consistent treatment.
Side Effects
Common side effects include genital yeast infections, urinary tract infections, and increased urination. Some patients experience thirst, dizziness, or mild dehydration. Rare but serious effects include diabetic ketoacidosis, severe urinary tract infections, or Fournier’s gangrene requiring immediate medical attention.
Warning
Forxiga 5mg may increase risk of diabetic ketoacidosis, even with normal blood glucose levels. Monitor for symptoms including nausea, vomiting, abdominal pain, or difficulty breathing. Increased risk of genital infections and severe urinary tract infections requires prompt treatment. Not recommended for type 1 diabetes or severe kidney impairment.
Pregnancy and Breastfeeding
Forxiga 5mg is not recommended during pregnancy due to potential kidney development risks in the fetus. Use effective contraception during treatment. Safety during breastfeeding is unknown, so alternative treatments should be considered for nursing mothers.
Interaction
- May increase risk of hypoglycemia when combined with insulin or sulfonylureas
- Diuretics may increase dehydration and low blood pressure risk
- May reduce effectiveness of lithium by increasing its excretion
- Possible interaction with certain blood pressure medications
- May affect digoxin levels requiring monitoring
Precaution
Use cautiously in patients with kidney disease, liver impairment, or history of genital infections. Monitor kidney function regularly. Ensure adequate hydration, especially during illness or hot weather. Temporarily discontinue before surgery or medical procedures requiring fasting. Check feet regularly for infections.
Important Information
Forxiga 5mg is not insulin and cannot treat diabetic ketoacidosis. Continue following diabetic diet and exercise recommendations. Regular blood glucose monitoring remains essential. Notify healthcare providers before surgeries or if experiencing persistent vomiting, dehydration, or unusual symptoms. Store at room temperature away from moisture and heat.
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