Loxagyl 200mg Tablet (Metronidazole) x100

Loxagyl 200mg Tablet contains Metronidazole, a nitroimidazole antibiotic effective against anaerobic bacteria and protozoa. This medication treats various infections including bacterial vaginosis, trichomoniasis, amoebiasis, and certain dental and abdominal infections.

Uses

Loxagyl 200mg treats anaerobic bacterial infections, protozoal infections like amoebiasis and trichomoniasis, bacterial vaginosis, and certain dental infections. It’s also used for Helicobacter pylori eradication and post-surgical infection prevention in high-risk patients.

Benefits

• Effective against anaerobic bacteria and protozoa
• Treats various types of infections simultaneously
• Rapid symptom relief within 24-48 hours
• Prevents infection recurrence when used correctly
• Well-established safety profile
• Available in multiple formulations
• Cost-effective treatment option
• Reduces complications from untreated infections
• Suitable for combination therapy protocols

How It Works

Loxagyl works by entering bacterial and protozoal cells where it’s converted to active metabolites. These metabolites damage DNA strands, preventing cell division and ultimately killing the microorganisms. It’s particularly effective against anaerobic organisms that thrive in oxygen-poor environments.

Dosage

Take Loxagyl with or after meals to reduce stomach irritation. Swallow tablets whole with water at evenly spaced intervals throughout the day.

Duration of Action

Loxagyl begins working within hours of administration, with peak blood levels reached in 1-2 hours. Symptom improvement typically occurs within 24-48 hours. The medication has a half-life of 6-8 hours, requiring multiple daily doses for sustained effectiveness.

Side Effects

Common side effects include nausea, metallic taste, headache, and mild gastrointestinal disturbances. Some patients experience dizziness, dark urine, or loss of appetite. Rare but serious effects include peripheral neuropathy with prolonged use or severe allergic reactions.

Warning

Avoid alcohol completely during treatment and for 48 hours after completion as it can cause severe nausea, vomiting, and flushing. Prolonged use may cause peripheral neuropathy. Loxagyl may interact with warfarin, increasing bleeding risk. Complete the full course even if symptoms improve.

Pregnancy and Breastfeeding

Loxagyl crosses the placenta and should be avoided in the first trimester unless essential. Use in second and third trimesters only when benefits outweigh risks. The medication passes into breast milk, so breastfeeding should be avoided during treatment and for 12-24 hours after completion.

Interaction

• Increases effects of warfarin and other anticoagulants
• May cause disulfiram-like reaction with alcohol consumption
• Potential interaction with phenytoin, affecting seizure control
• May increase lithium levels in blood
• Possible interaction with certain antacids reducing absorption
• Could interfere with certain laboratory tests

Precaution

Use with caution in patients with liver disease, blood disorders, or neurological conditions. Monitor for signs of peripheral neuropathy during prolonged treatment. Avoid in patients with known hypersensitivity to nitroimidazoles. Inform healthcare provider about all medications and supplements being taken.

Important Information

Loxagyl is a prescription antibiotic requiring medical supervision. Sexual partners should be treated simultaneously for sexually transmitted infections. Store at room temperature away from moisture and heat. Dark urine during treatment is normal and harmless. Do not share medication with others even if they have similar symptoms.