Treviamet 50mg/1000mg Tablet (Sitagliptin) x35

Treviamet 50mg/1000mg Tablet combines Sitagliptin (50mg) and Metformin HCL (1000mg) for type 2 diabetes management. This dual-action formula helps control blood sugar levels through complementary mechanisms in adults with diabetes.

Uses

Treviamet Tablet treats type 2 diabetes mellitus in adults when diet and exercise alone are insufficient. It’s prescribed when single-agent therapy doesn’t provide adequate glycemic control or as initial combination therapy in patients with high baseline blood sugar levels.

Benefits

• Provides dual mechanism blood sugar control
• Reduces fasting and post-meal glucose levels
• Lowers HbA1c levels effectively
• Decreases risk of diabetes complications
• May promote modest weight loss
• Reduces insulin resistance
• Improves beta-cell function
• Convenient once or twice daily dosing
• Lower risk of hypoglycemia compared to some diabetes medications

How It Works

Sitagliptin, a DPP-4 inhibitor, increases insulin release and decreases glucagon when blood sugar is elevated. Metformin reduces glucose production in the liver, decreases intestinal glucose absorption, and improves insulin sensitivity in muscles. Together, they provide comprehensive blood sugar management.

Dosage

Take Treviamet with meals to reduce stomach upset. Swallow tablets whole with water. Do not crush or chew.

Duration of Action

Treviamet begins working within hours of administration. Metformin effects develop gradually over days to weeks, while Sitagliptin provides immediate glucose-dependent insulin enhancement. Maximum therapeutic effects are typically achieved within 2-3 weeks of consistent use.

Side Effects

Common side effects include nausea, diarrhea, stomach upset, and metallic taste from Metformin. Sitagliptin may cause headache, upper respiratory tract infections, or muscle pain. Most side effects are mild and improve with continued use. Lactic acidosis is a rare but serious complication.

Warning

Risk of lactic acidosis, especially in patients with kidney or liver problems, heart failure, or during illness with dehydration. Stop Treviamet before surgery or contrast imaging procedures. Not for type 1 diabetes or diabetic ketoacidosis. Monitor kidney function regularly during treatment.

Pregnancy and Breastfeeding

Treviamet is not recommended during pregnancy as insulin is preferred for blood sugar control. Discontinue before planned pregnancy. Safety during breastfeeding is not established. Most guidelines recommend insulin therapy during pregnancy and lactation for optimal maternal and fetal outcomes.

Interaction

• Increased risk of lactic acidosis with alcohol consumption
• May interact with contrast dyes used in imaging procedures
• Possible interaction with certain blood pressure medications
• May affect absorption of vitamin B12 with long-term use
• Potential interaction with carbonic anhydrase inhibitors

Precaution

Use with caution in patients with kidney disease, liver problems, heart failure, or chronic lung disease. Monitor kidney function before starting and regularly during treatment. Avoid excessive alcohol consumption. Stop during acute illness, dehydration, or before surgical procedures requiring anesthesia.

Important Information

Treviamet is part of comprehensive diabetes management including diet, exercise, and regular monitoring. Check blood sugar as directed by your healthcare provider. Carry glucose tablets for low blood sugar episodes. Store at room temperature away from moisture and heat. Regular medical follow-ups are essential for monitoring effectiveness and side effects.