Dogrel-75 Tablet (Clopidogrel) x30

Dogrel-75 Tablet contains Clopidogrel, a potent antiplatelet medication that prevents blood clot formation in arteries. By inhibiting platelet aggregation, it effectively reduces the risk of serious cardiovascular complications for patients with cardiovascular risk factors.

Uses

Dogrel-75 Tablet is primarily used for prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease. It is also used for prevention of atherothrombotic and thromboembolic events in patients with atrial fibrillation who cannot take oral anticoagulation therapy.

Benefits

• Reduces risk of heart attacks, strokes, and peripheral arterial disease
• Prevents blood clot formation in arteries
• Provides effective long-term cardiovascular protection
• Suitable for patients with recent cardiac events
• Offers alternative to oral anticoagulation therapy
• Helps manage cardiovascular risk in vulnerable patients
• Demonstrated efficacy in clinical trials
• Once-daily dosing for better compliance

How It Works

Dogrel-75 Tablet works by inhibiting the binding of adenosine diphosphate (ADP) to its platelet receptor, thus preventing ADP-mediated platelet activation and aggregation. This mechanism reduces platelet clumping, which decreases the risk of blood clot formation in arteries that can lead to serious cardiovascular events.

Duration of Action

The antiplatelet effects begin within 2 hours of taking the first dose. Maximum platelet inhibition occurs after 4-7 days of regular dosing. The effects can last for 5-7 days after discontinuation due to the irreversible nature of platelet inhibition.

Dosage

Warnings

Increased risk of bleeding is significant, especially during surgery or trauma. Discontinue treatment 5-7 days before planned surgery. Monitor for signs of unusual bleeding or bruising. Requires immediate medical attention for severe bleeding events.

Side Effects

Common side effects include bleeding tendencies such as easy bruising and prolonged bleeding time. Patients may experience gastrointestinal disturbances, skin reactions, and headaches. Most side effects are mild and manageable.

Pregnancy and Breastfeeding

Use during pregnancy should be based on careful assessment of benefits versus risks. Not recommended during breastfeeding due to potential risks to the infant. Consult healthcare provider for guidance.

Interactions

• Increases bleeding risk with anticoagulants
• May interact with NSAIDs and aspirin
• Reduced effectiveness with certain proton pump inhibitors
• Potential interactions with other antiplatelet drugs
• May be affected by certain antidepressants

Precautions

Monitor for signs of bleeding. Regular blood count checks may be needed. Avoid activities with high risk of injury. Report any unusual bleeding or bruising to healthcare provider immediately.

Important Information

Take consistently at the same time each day. Do not stop medication without consulting healthcare provider. Carry medical identification indicating use of antiplatelet medication. Store at room temperature away from moisture and heat.